Principal Scientist
Posted on: 10/15/2024
Taipei
Permanent
Pharmaceutical and Healthcare
We are looking for a skilled and enthusiastic Principal Scientist to join our dynamic team in Taipei, supporting the development of cutting-edge RNA therapies targeting critical health challenges. Our Taipei lab specializes in precision-slice liver cultures, conducting deep phenotyping of liver tissues from diseased donors to analyze their responses to advanced RNA treatments through imaging, functional assays, and single-cell sequencing. The position will lead efforts to innovate within ex-vivo liver slice and primary human cell culture systems. The ideal candidate should thrive in a fast-paced environment, collaborate with the team, and mentor junior scientists. Expertise in ex-vivo tissue systems, 3D organoid cultures, and RNAi screening is highly desirable. PhD holders or Post Docs aiming to transition into industrial research are encouraged to apply,
Responsibilities:
- Develop and implement innovative cell and tissue culture techniques for liver fibrosis and regeneration studies.
- Design and manage large-scale RNAi screens in liver tissues and cells to uncover novel targets.
- Collaborate with international teams across US, UK, and Taiwan sites.
- Lead and support junior scientists in the lab.
- Manage external collaborations and suppliers.
- Present experimental findings to internal and external teams.
- Participate in global and cross-site projects.
Qualifications:
- PhD in biological sciences with a proven track record of scientific achievements, such as first-author publications or patents.
- Preferable experience in biotech startups or industry.
- Expertise in 3D tissue cultures, organ-on-chip systems, RNAi screens, and high-content imaging.
- Strong background in biology and cellular model development.
- Experience with high-throughput workflows and large-scale screens.
- Highly organized with excellent problem-solving skills.
- Ability to work independently and in a collaborative environment.
- Proactive with strong attention to detail and ability to handle multiple projects simultaneously.
- Strong communication skills, with fluency in English.
- Flexibility and adaptability in a fast-paced, evolving environment.
- Desirable: proficiency in data analysis with R.